Nature2026
A deep-learning framework reveals whole-body perturbations at cell level
Doris Kaltenecker et al.
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Nature · 2026
MouseMapper
Whole-body nervous & immune architecture in 3D
Whole-body nerve architecture
Whole-body reconstructions of normal (left) and obese (right) UCHL1-EGFP mice. Peripheral nerves (UCHL1-EGFP+) are shown in green, bones and organs are shown in red (propidium iodide labeled) and muscle (autofluorescence) is shown in blue.
Foundation-model deep learning segments and quantifies whole-body nervous and immune systems in cleared mice — revealing systemic remodeling in obesity and disease.
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Lab contributors
Current Ertürk Lab members linked to this project.
Doris Kaltenecker
Postdoc
Ying Chen
Ph.D. Candidate
Luciano Höher
Virtual Reality Expert
Mihail Todorov
Postdoc
Sena Turhan
Ph.D. Candidate
Louis Kümmerle
Postdoc
Denise Jeridi
Technical Assistant
Laurent Simons
Ph.D. Candidate
Farida Hellal
Co-deputy
Markus Elsner
Co-deputy
Harsharan S. Bhatia
Omics Technologies Team Leader
Ali Maximilian Ertürk
Director
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